Rubella virus.

Sequence and Phylogenetic Analysis of Wild Type Rubella virus isolated in Iran

Background and Aims: Rubella virus is a human pathogen that causes congenital rubella syndrome (CRS) when infection occurs during early pregnancy. Vaccination programs have been remarkably successful in controlling natural rubella infection and CRS. Moreover, ongoing surveillance for all cases of rubella and CRS is a vital component of a prevention program. Although the WHO recommends the use o...

Isolation of Rubella Virus from Patients with Progressive Rubella Pan-Encephalitis

During a period of 7 years (1997-2003) we were received pairs of serum and CSF of 27 suspicious clinically cases from neurology department of several hospitals in Tehran. Among them 7 were serologically positive for progressive rubella panencephalitis (PRPE) and 2 were positive for sub acute sclerosing panencephalitis (SSPE). Rubella virus was isolated from 4 of 7 serologically positive cases o...

Use of human diploid cell MRC - 5, for production of Measles and Rubella virus vaccines

بررسی وضعیت سرولوژیک ویروس سرخجه در نمونه های خون بند ناف نوزادان تازه متولد شده در بیمارستانهای وابسته به دانشگاه علوم پزشکی تهران

Introduction & Objective: Rubella is a disease caused by the rubella virus and is usually mild and self-limiting. Infection of a developing fetus is serious and important because the child may be born with congenital rubella syndrome. Its symptoms include mental retardation, heart defects, cataract, etc. In 2003, mass vaccination against measles and rubella in individuals 5-25 years old was d...

Estimation of the Cultured Cells’ Volume and Surface Area: Application of Stereological Methods on Vero Cells Infected by Rubella Virus

Background: Morphological changes of the cells infected with rubella virus cannot be observed easily. Estimation of the size of the cultured cells can be a valuable parameter in this condition. This study was conducted to find answers to the following questions:How much time after infection with rubella virus, the volume and surface area of the Vero cells and their nuclei get started to change?...

Evaluation of Antibodies against Rubella Virus in a Mass Campaign Vaccination in Tehran, Iran

Background and Aims: Vaccine is available, but fetal infection with rubella virus is still a main cause of congenital birth defects and mental retardation in many countries. Mass vaccination campaigns and Expanded Program of Immunization (EPI) have increased vaccine coverage in the world with a substantial impact on the reduction of rubella infections, such as Congenital Rubella Syndrome (CRS)....